GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PTGS2 | increases expression | EXP | | 6480464 | CTD | deoxynivalenol results in increased expression of PTGS2 mRNA; deoxynivalenol results in increased expression of PTGS2 protein | PMID:20347963 PMID:20633634 PMID:27757495 | PTGS2 | multiple interactions | EXP | | 6480464 | CTD | Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein] | PMID:20347963 | PTGS2 | increases expression | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | deoxynivalenol results in increased expression of PTGS2 mRNA; deoxynivalenol results in increased expression of PTGS2 protein | PMID:11922776 PMID:12377986 PMID:12649040 PMID:14514436 PMID:15570035 PMID:21873375 PMID:24937323 PMID:32416088 | PTGS2 | increases stability | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | deoxynivalenol results in increased stability of PTGS2 mRNA | PMID:12377986 | PTGS2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Docosahexaenoic Acids inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; Indomethacin promotes the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; PTGS2 protein affects the reaction [deoxynivalenol results in increased expression of IL6 protein]; Ro 31-8220 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [deoxynivalenol results in increased stability of PTGS2 mRNA] | PMID:11922776 PMID:12377986 PMID:12649040 PMID:15570035 PMID:32416088 | |
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