GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HMOX1 | decreases expression | EXP | | 6480464 | CTD | Tretinoin results in decreased expression of HMOX1 mRNA | PMID:16054129 | HMOX1 | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of HMOX1 mRNA | PMID:16882163 PMID:23830798 | HMOX1 | multiple interactions | EXP | | 6480464 | CTD | RARA gene mutant form inhibits the reaction [Tretinoin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]]; Tretinoin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Tretinoin inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Tretinoin inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein] | PMID:25003661 PMID:30309986 | HMOX1 | increases expression | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | Tretinoin results in increased expression of HMOX1 mRNA | PMID:20117194 | HMOX1 | multiple interactions | ISO | Hmox1 (Mus musculus) | 6480464 | CTD | [bisphenol F co-treated with Tretinoin] results in decreased expression of HMOX1 mRNA; Tretinoin inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]]; Tretinoin promotes the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA] | PMID:29964319 PMID:30951980 | | ||||||||||||||||||||||
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