GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp3a2 | decreases expression | EXP | | 6480464 | CTD | Oxycodone results in decreased expression of CYP3A2 mRNA; Oxycodone results in decreased expression of CYP3A2 protein | PMID:20487198 | Cyp3a2 | multiple interactions | EXP | | 6480464 | CTD | Oxycodone inhibits the reaction [CYP3A2 protein results in increased hydroxylation of Testosterone] | PMID:20487198 | Cyp3a2 | affects metabolic processing | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | CYP3A4 protein alternative form affects the metabolism of Oxycodone | PMID:33393779 | Cyp3a2 | multiple interactions | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | telithromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Oxycodone] | PMID:19755414 | |
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