GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp3a2 | decreases activity | EXP | | 6480464 | CTD | Arsenic results in decreased activity of CYP3A4 protein | PMID:19932728 | Cyp3a2 | multiple interactions | EXP | | 6480464 | CTD | Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP3A4 protein] | PMID:19932728 | Cyp3a2 | multiple interactions | ISO | CYP3A4 (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP3A4 mRNA; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CYP3A4 mRNA | PMID:35747940 | | ||||||||||||||||||||||
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