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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708379
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a2
Name: cytochrome P450, family 3, subfamily a, polypeptide 2
Acc ID: CHEBI:45304
Term: rifapentine
Definition: A N-iminopiperazine that has formula C47H64N4O12.
Chemical ID: MESH:C018421
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a2increases expressionISOCYP3A4 (Homo sapiens)6480464CTDrifapentine results in increased expression of CYP3A4 mRNAPMID:16837568 PMID:21856291
Cyp3a2multiple interactionsISOCYP3A4 (Homo sapiens)6480464CTDAADAC mRNA affects the reaction [rifapentine results in increased expression of CYP3A4 mRNA]PMID:21856291
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