GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp3a2 | decreases expression | EXP | | 6480464 | CTD | 1-Naphthylisothiocyanate results in decreased expression of CYP3A2 mRNA | PMID:26365562 PMID:30723492 | Cyp3a2 | increases expression | EXP | | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of CYP3A4 mRNA; 1-Naphthylisothiocyanate results in increased expression of CYP3A4 protein | PMID:32198087 | Cyp3a2 | multiple interactions | EXP | | 6480464 | CTD | ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP3A4 mRNA]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP3A4 protein]; Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP3A4 mRNA]; Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of CYP3A4 protein] | PMID:32198087 | | ||||||||||||||||||||||
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