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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:9429
Term: tectorigenin
Definition: A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively.
Chemical ID: MESH:C120039
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1multiple interactionsISOSrebf1 (Mus musculus)6480464CTDtectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein]PMID:35390440
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