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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:35546
Term: perfluorodecanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated decanoic acid.
Chemical ID: MESH:C036567
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1increases expressionISOSrebf1 (Mus musculus)6480464CTDperfluorodecanoic acid results in increased expression of SREBF1 mRNAPMID:36423729
Srebf1multiple interactionsISOSrebf1 (Mus musculus)6480464CTDbenzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [perfluorodecanoic acid results in increased expression of SREBF1 mRNA]PMID:36423729
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