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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1affects expressionISOSrebf1 (Mus musculus)6480464CTDArsenic affects the expression of SREBF1 mRNAPMID:36463740
Srebf1decreases expressionISOSrebf1 (Mus musculus)6480464CTDArsenic results in decreased expression of SREBF1 proteinPMID:36463740
Srebf1multiple interactionsISOSrebf1 (Mus musculus)6480464CTD[APOE protein affects the susceptibility to Arsenic] which results in increased expression of SREBF1 proteinPMID:22719926
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