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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl5
Name: C-C motif chemokine ligand 5
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl5increases expressionISOCCL5 (Homo sapiens)6480464CTDdeoxynivalenol results in increased expression of CCL5 mRNAPMID:27757495
Ccl5increases expressionISOCcl5 (Mus musculus)6480464CTDdeoxynivalenol results in increased expression of CCL5 mRNAPMID:22968694 PMID:35925383
Ccl5multiple interactionsISOCcl5 (Mus musculus)6480464CTDbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in increased expression of CCL5 mRNA]PMID:35925383
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