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GENE - TERM ANNOTATION REPORT

RGD ID: 68466
Species: Mus musculus
RGD Object: Gene
Symbol: Gpr12
Name: G-protein coupled receptor 12
Acc ID: GO:0007189
Term: adenylate cyclase-activating G protein-coupled receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpr12involved_inIBAPANTHER:PTN002733616 or ZFIN:ZDB-GENE-021223-2 or MGI:1333809 or UniProtKB:Q01718 or UniProtKB:F1STP7 or ZFIN:ZDB-GENE-030502-2 or UniProtKB:P33032 or UniProtKB:P41968 or UniProtKB:P32245 or UniProtKB:Q017262290270GO_Central GO_REF:0000033
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