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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631408
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp8
Name: matrix metallopeptidase 8
Acc ID: CHEBI:64342
Term: 3-hydroxypicolinic acid
Definition: A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.
Chemical ID: MESH:C049246
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp8decreases activityISOMMP8 (Homo sapiens)6480464CTD3-hydroxypicolinic acid results in decreased activity of MMP8 proteinPMID:21189019
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