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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628896
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Angpt1
Name: angiopoietin 1
Acc ID: CHEBI:29678
Term: sodium arsenite
Definition: An inoganic sodium salt with formula with formula NaAsO2.
Chemical ID: MESH:C017947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Angpt1decreases expressionISOANGPT1 (Homo sapiens)6480464CTDsodium arsenite results in decreased expression of ANGPT1 mRNAPMID:34032870
Angpt1decreases secretionISOANGPT1 (Homo sapiens)6480464CTDsodium arsenite results in decreased secretion of ANGPT1 proteinPMID:19622383
Angpt1increases expressionISOANGPT1 (Homo sapiens)6480464CTDsodium arsenite results in increased expression of ANGPT1 mRNA; sodium arsenite results in increased expression of ANGPT1 proteinPMID:19622383 PMID:25493608
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