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GENE - TERM ANNOTATION REPORT

RGD ID: 628758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptk2b
Name: protein tyrosine kinase 2 beta
Acc ID: GO:0043197
Term: dendritic spine
Definition: A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
Definition Source(s): GOC:nln
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptk2bis_active_inIBAPANTHER:PTN000700474 or Ptk2 (Rattus norvegicus) or Ptk2b (Rattus norvegicus)1600115GO_CentralGO_REF:0000033

GO_REF:0000033
Ptk2blocated_inIDA 12050116SynGOPMID:22973009

 
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