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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628649
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mc2r
Name: melanocortin 2 receptor
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mc2rincreases expressionISOMC2R (Homo sapiens)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of MC2R mRNAPMID:25765474
Mc2rmultiple interactionsISOMC2R (Homo sapiens)6480464CTD[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of MC2R mRNA; [Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of MC2R mRNAPMID:25765474
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