GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr1i3 | affects metabolic processing | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | NR1I3 protein affects the metabolism of Parathion | PMID:20573718 | Nr1i3 | decreases response to substance | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | NR1I3 results in decreased susceptibility to Parathion | PMID:20573718 | Nr1i3 | increases activity | ISO | NR1I3 (Homo sapiens) | 6480464 | CTD | Parathion results in increased activity of NR1I3 protein | PMID:28927721 | Nr1i3 | increases expression | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | Parathion results in increased expression of NR1I3 mRNA | PMID:34813904 | Nr1i3 | multiple interactions | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | [NR1I3 protein affects the metabolism of Parathion] which affects the chemical synthesis of 4-nitrophenol; [NR1I3 protein affects the metabolism of Parathion] which affects the chemical synthesis of Paraoxon; Parathion binds to and results in increased activity of NR1I3 protein; Parathion inhibits the reaction [Androstane-3,17-diol binds to and results in decreased activity of NR1I3 protein] | PMID:18832183 PMID:20573718 | | ||||||||||||||||||||||
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