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GENE - TERM ANNOTATION REPORT

RGD ID: 621130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dync1li2
Name: dynein, cytoplasmic 1 light intermediate chain 2
Acc ID: GO:0005868
Term: cytoplasmic dynein complex
Definition: Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
Definition Source(s): GOC:cilia, GOC:hla, GOC:krc, GOC:mah, PMID:12600311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dync1li2part_ofIBAFB:FBgn0030276 or PANTHER:PTN000293992 or PomBase:SPAC458.04c or UniProtKB:Q9Y6G91600115GO_CentralGO_REF:0000033

GO_REF:0000033
Dync1li2part_ofIEAUniRule:UR0009957621600115UniProtGO_REF:0000104

GO_REF:0000104
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