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GENE - TERM ANNOTATION REPORT

RGD ID: 621017
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lyn
Name: LYN proto-oncogene, Src family tyrosine kinase
Acc ID: GO:0070373
Term: negative regulation of ERK1 and ERK2 cascade
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Definition Source(s): GOC:add, ISBN:0121245462, ISBN:0896039986
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lyninvolved_inISOLyn (Mus musculus)1624291RGD MGI:2687173 PMID:14525964 MGI:3044099 PMID:14726379

MGI:2687173 MGI:3044099 PMID:14525964 PMID:14726379
Lyninvolved_inISSUniProtKB:P259111600115UniProtGO_REF:0000024

GO_REF:0000024
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