GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pik3ca | increases expression | ISO | PIK3CA (Homo sapiens) | 6480464 | CTD | Niclosamide results in increased expression of PIK3CA mRNA | PMID:29843133 | Pik3ca | multiple interactions | ISO | PIK3CA (Homo sapiens) | 6480464 | CTD | Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] | PMID:27542212 | |
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