GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | decreases expression | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | hydroquinone results in decreased expression of NFE2L2 mRNA | PMID:31967339 | Nfe2l2 | increases activity | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased activity of NFE2L2 promoter | PMID:21643505 | Nfe2l2 | increases expression | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | hydroquinone results in increased expression of NFE2L2 protein | PMID:28645578 PMID:32141582 PMID:35123993 | Nfe2l2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | hydroquinone results in increased expression of NFE2L2 mRNA; hydroquinone results in increased expression of NFE2L2 protein | PMID:23290930 | Nfe2l2 | multiple interactions | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of and affects the localization of NFE2L2 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; 2-tert-butylhydroquinone promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; ferric chloride promotes the reaction [hydroquinone results in increased expression of NFE2L2 protein]; hydroquinone affects the localization of and results in increased degradation of NFE2L2 protein; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; hydroquinone promotes the reaction [NFE2L2 protein binds to SRC protein]; hydroquinone results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of GSS protein]; NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein]; S-allylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein] | PMID:21059386 PMID:21643505 PMID:23290930 PMID:28645578 PMID:32141582 PMID:35123993 PMID:36646296 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 mRNA affects the reaction [hydroquinone results in increased expression of HMOX1 protein] | PMID:23290930 | | ||||||||||||||||||||||
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