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GENE - TERM ANNOTATION REPORT

RGD ID: 62030
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myh7
Name: myosin heavy chain 7
Acc ID: DOID:9004616
Term: Left Ventricular Hypertrophy
Definition: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
Definition Source(s): MESH:D017379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myh7 IEP 12792943RGDmRNA, protein:increased expression:heart left ventricle 
Myh7 ISOMYH7 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Increased left ventricular wall thickness | ClinVar Annotator: match by term: Left ventricular hypertrophyPMID:10900182 PMID:15322983 PMID:16754800 PMID:17372140 PMID:17947214 PMID:19808347 PMID:19864899 PMID:20031602 PMID:20624503 PMID:20733148 PMID:20800588 PMID:2136805 PMID:21499742 PMID:21511876 PMID:22763267 PMID:22918376 PMID:22958901 PMID:23281406 PMID:23299917 PMID:23349452 PMID:23396983 PMID:23426552 PMID:23707328 PMID:23861362 PMID:24033266 PMID:24055113 PMID:24111713 PMID:24119082 PMID:24503780 PMID:25125180 PMID:25163546 PMID:25351510 PMID:25524337 PMID:25666907 PMID:25741868 PMID:26332594 PMID:26743238 PMID:28193612 PMID:28265379 PMID:28416588 PMID:28492532 PMID:28807990 PMID:28971120 PMID:29300372 PMID:29915098 PMID:30775854 PMID:31006259 PMID:3203908 PMID:7883988 PMID:7909436 PMID:8614836 PMID:8981935 PMID:9884344
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