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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620190
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Becn1
Name: beclin 1
Acc ID: CHEBI:17594
Term: hydroquinone
Definition: A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Chemical ID: MESH:C031927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Becn1increases expressionISOBECN1 (Homo sapiens)6480464CTDhydroquinone results in increased expression of BECN1 mRNA; hydroquinone results in increased expression of BECN1 proteinPMID:28263894 PMID:35302183 PMID:37148176
Becn1multiple interactionsISOBECN1 (Homo sapiens)6480464CTDPARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]; SIRT1 protein inhibits the reaction [hydroquinone results in increased expression of BECN1 mRNA]PMID:28263894
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