GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pten | multiple interactions | EXP | | 6480464 | CTD | celastrol inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein]; PTEN protein promotes the reaction [celastrol inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]]; PTEN protein promotes the reaction [celastrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]]; PTEN protein promotes the reaction [celastrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]] | PMID:24111524 | | ||||||||||||||||||||||
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