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GENE - TERM ANNOTATION REPORT

RGD ID: 61958
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S1pr1
Name: sphingosine-1-phosphate receptor 1
Acc ID: GO:0003376
Term: sphingosine-1-phosphate receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway initiated by sphingosine-1-phosphate binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:ascb_2009, GOC:signaling, PMID:14592418, PMID:22001186, Reactome:R-HSA-419428
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S1pr1involved_inISOS1PR1 (Homo sapiens)1624291RGD PMID:22344443

PMID:22344443
S1pr1involved_inISOS1pr1 (Mus musculus)1624291RGD MGI:2151313 PMID:11032855

MGI:2151313 PMID:11032855
S1pr1involved_inIBAMGI:1096355 or PANTHER:PTN002733784 or UniProtKB:P214531600115GO_CentralGO_REF:0000033

GO_REF:0000033
S1pr1involved_inISSUniProtKB:O085301600115UniProtGO_REF:0000024

GO_REF:0000024
S1pr1involved_inISSUniProtKB:P214531600115UniProtGO_REF:0000024

GO_REF:0000024
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