GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | multiple interactions | EXP | | 6480464 | CTD | [vorinostat co-treated with MYC protein] results in increased cleavage of CASP9 protein | PMID:17331788 | Casp9 | increases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | vorinostat results in increased activity of CASP9 protein | PMID:15173093 PMID:18025281 PMID:19737941 | Casp9 | increases cleavage | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | vorinostat results in increased cleavage of CASP9 protein | PMID:15897598 | Casp9 | multiple interactions | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | [Bortezomib co-treated with vorinostat] results in increased activity of CASP9 protein; [Bortezomib co-treated with vorinostat] results in increased cleavage of and results in increased activity of CASP9 protein; [vorinostat co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein; Bortezomib promotes the reaction [vorinostat results in increased activity of CASP9 protein] | PMID:12893773 PMID:15173093 PMID:18005386 PMID:18641367 PMID:19643600 | | ||||||||||||||||||||||
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