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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3648
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sdc1
Name: syndecan 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sdc1decreases expressionISOSDC1 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of SDC1 mRNAPMID:19128835
Sdc1decreases response to substanceISOSDC1 (Homo sapiens)6480464CTDSDC1 protein results in decreased susceptibility to Arsenic TrioxidePMID:20707922
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