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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scg2
Name: secretogranin II
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scg2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of SCG2 mRNAPMID:25181051 PMID:30816183 PMID:32528016 PMID:34947998
Scg2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SCG2 mRNAPMID:36041667
Scg2decreases expressionISOScg2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of SCG2 mRNAPMID:32156529
Scg2increases expressionISOSCG2 (Homo sapiens)6480464CTDbisphenol A analog results in increased expression of SCG2 mRNAPMID:32387340
Scg2increases methylationISOSCG2 (Homo sapiens)6480464CTDbisphenol A results in increased methylation of SCG2 genePMID:31601247
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