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GENE - TERM ANNOTATION REPORT

RGD ID: 3307
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pfkfb1
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Acc ID: GO:0006003
Term: fructose 2,6-bisphosphate metabolic process
Definition: The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.
Definition Source(s): ISBN:0198506732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pfkfb1involved_inISOPFKFB1 (Homo sapiens)1624291RGD PMID:2837207

PMID:2837207
Pfkfb1 TAS 729562RGD  
Pfkfb1involved_inIBAPANTHER:PTN000743282 or Pfkfb3 (Rattus norvegicus) or SGD:S000001369 or SGD:S000005496 or TAIR:locus:2007367 or UniProtKB:P161181600115GO_CentralGO_REF:0000033

GO_REF:0000033
Pfkfb1involved_inIEAInterPro:IPR0030941600115InterProGO_REF:0000002

GO_REF:0000002
Pfkfb1involved_inISSUniProtKB:P161181600115UniProtGO_REF:0000024

GO_REF:0000024
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