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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3234
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Oprm1
Name: opioid receptor, mu 1
Acc ID: CHEBI:29133
Term: dextrorphan
Definition: A morphinane alkaloid that has formula C17H23NO.
Chemical ID: MESH:D003917
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oprm1affects bindingEXP 6480464CTDDextrorphan binds to OPRM1 proteinPMID:7562497
Oprm1multiple interactionsEXP 6480464CTD[Dextrorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Dextrorphan binds to OPRM1 protein] which results in decreased uptake of SerotoninPMID:7562497
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