GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1b | multiple interactions | EXP | | 6480464 | CTD | [Genistein co-treated with Methoxychlor] results in decreased expression of IL1B mRNA; Genistein inhibits the reaction [Galactosamine results in increased expression of IL1B mRNA]; Genistein inhibits the reaction [IL1B protein results in increased activity of TAC1 protein]; Genistein inhibits the reaction [IL1B protein results in increased expression of TAC1 mRNA]; Genistein inhibits the reaction [lipoteichoic acid results in increased expression of IL1B] | PMID:14622206 PMID:20685402 PMID:21782745 PMID:25620059 | Il1b | decreases expression | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Genistein results in decreased expression of IL1B mRNA | PMID:20816778 | Il1b | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Genistein analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein]; Genistein inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]; Genistein inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]; Genistein inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA]; Genistein inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA]; Genistein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Genistein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein] | PMID:12072388 PMID:22981962 PMID:24491678 PMID:25447760 PMID:28259689 | Il1b | multiple interactions | ISO | IL1B (Homo sapiens) | 6480464 | CTD | Genistein inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein] | PMID:18377686 | | ||||||||||||||||||||||
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