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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2737
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grin2a
Name: glutamate ionotropic receptor NMDA type subunit 2A
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grin2aaffects splicingEXP 6480464CTDValproic Acid affects the splicing of GRIN2A mRNAPMID:29427782
Grin2adecreases expressionEXP 6480464CTDValproic Acid results in decreased expression of GRIN2A mRNAPMID:29427782
Grin2aincreases expressionEXP 6480464CTDValproic Acid results in increased expression of GRIN2A proteinPMID:17675408
Grin2aaffects expressionISOGRIN2A (Homo sapiens)6480464CTDValproic Acid affects the expression of GRIN2A mRNAPMID:25979313
Grin2adecreases expressionISOGRIN2A (Homo sapiens)6480464CTDValproic Acid results in decreased expression of GRIN2A mRNAPMID:24935251
Grin2aincreases expressionISOGrin2a (Mus musculus)6480464CTDValproic Acid results in increased expression of GRIN2A mRNAPMID:36113784
Grin2aincreases expressionISOGRIN2A (Homo sapiens)6480464CTDValproic Acid results in increased expression of GRIN2A mRNAPMID:23179753 PMID:27188386 PMID:28001369
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