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GENE - TERM ANNOTATION REPORT

RGD ID: 2533
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Edn2
Name: endothelin 2
Acc ID: GO:0014826
Term: vein smooth muscle contraction
Definition: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.
Definition Source(s): GOC:mtg_muscle, MA:0000715, MSH:D014680
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edn2involved_inISOEDN2 (Homo sapiens)1624291RGD PMID:8982507 PMID:9422810

PMID:8982507 PMID:9422810
Edn2involved_inIEAUniProtKB:P20800 or ensembl:ENSP000003616681600115EnsemblGO_REF:0000107

GO_REF:0000107
Edn2involved_inIBAPANTHER:PTN000356323 or UniProtKB:P05305 or UniProtKB:P14138 or UniProtKB:P208001600115GO_CentralGO_REF:0000033

GO_REF:0000033
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