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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2368
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cnp
Name: 2',3'-cyclic nucleotide 3' phosphodiesterase
Acc ID: CHEBI:8058
Term: phencyclidine
Definition: A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
Chemical ID: MESH:D010622
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cnpdecreases expressionISOCnp (Mus musculus)6480464CTDPhencyclidine results in decreased expression of CNP mRNAPMID:17266109
Cnpincreases expressionISOCnp (Mus musculus)6480464CTDPhencyclidine results in increased expression of CNP mRNAPMID:17266109
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