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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:17948
Term: (+)-taxifolin
Definition: A taxifolin that has (2R,3R)-configuration.
Chemical ID: MESH:C003377
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catmultiple interactionsEXP 6480464CTDFluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in decreased expression of CAT protein]]; taxifolin analog inhibits the reaction [Dietary Fats results in decreased activity of CAT protein]; taxifolin inhibits the reaction [Acetic Acid results in increased activity of CAT protein]; taxifolin inhibits the reaction [bisphenol A results in decreased expression of CAT protein]; taxifolin inhibits the reaction [Dibutyl Phthalate results in decreased expression of CAT mRNA]; taxifolin inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CAT mRNA]; taxifolin inhibits the reaction [Rotenone results in decreased activity of CAT protein]; taxifolin promotes the reaction [Fluvastatin inhibits the reaction [bisphenol A results in decreased expression of CAT protein]]PMID:30372826 PMID:32525071 PMID:33741339 PMID:35187747 PMID:35465754 PMID:36198370
Catdecreases activityISOCAT (Homo sapiens)6480464CTDtaxifolin results in decreased activity of CAT proteinPMID:38574953
Catmultiple interactionsISOCAT (Homo sapiens)6480464CTDtaxifolin inhibits the reaction [Hydrogen Peroxide results in increased activity of CAT protein]PMID:38574953
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