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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:38845
Term: profenofos
Definition: An organophosphate insecticide that has formula C11H15BrClO3PS.
Chemical ID: MESH:C024273
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISOCasp3 (Mus musculus)6480464CTD[cypermethrin co-treated with Chlorpyrifos co-treated with profenofos] results in increased cleavage of CASP3 proteinPMID:21987380
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