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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2088
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh3a1
Name: aldehyde dehydrogenase 3 family, member A1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh3a1decreases expressionISOALDH3A1 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of ALDH3A1 mRNAPMID:29501571
Aldh3a1increases methylationISOALDH3A1 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of ALDH3A1 genePMID:29501571
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