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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akt1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:34157
Term: 14,15-EET
Definition: An EET obtained by formal epoxidation of the 14,15-double bond of arachidonic acid.
Chemical ID: MESH:C046782
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases phosphorylationISOAKT1 (Homo sapiens)6480464CTD14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of AKT1 proteinPMID:16286479
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