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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2032
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adam10
Name: ADAM metallopeptidase domain 10
Acc ID: CHEBI:34440
Term: 4-nonylphenol
Definition: A member of the class of phenols that is phenol which is para-substituted with a nonyl group.
Chemical ID: MESH:C041594
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adam10multiple interactionsISOAdam10 (Mus musculus)6480464CTDADAM10 protein affects the reaction [[ADAM17 protein affects the susceptibility to 4-nonylphenol] which affects the secretion of BTC protein]; ADAM10 protein affects the reaction [ADAM17 protein affects the reaction [4-nonylphenol results in increased secretion of HBEGF protein]]; ADAM10 protein affects the reaction [ADAM17 protein affects the reaction [4-nonylphenol results in increased secretion of TGFA protein]]PMID:28703301
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