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GENE - TERM ANNOTATION REPORT

RGD ID: 18904985
Species: Heterocephalus glaber
RGD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: DOID:1909
Term: melanoma
Definition: A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Melanoma "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/22123420 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chek2 ISOCHEK2 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: MelanomaPMID:12533788 PMID:15087378 PMID:15095295 PMID:15492928 PMID:15810020 PMID:17085682 PMID:19030985 PMID:20417869 PMID:21876083 PMID:22058216 PMID:23296741 PMID:24713400 PMID:25085752 PMID:25525159 PMID:25583358 PMID:25741868 PMID:25980754 PMID:26084796 PMID:26446916 PMID:26467025 PMID:26681312 PMID:26689913 PMID:26822949 PMID:26845104 PMID:27153395 PMID:27616075 PMID:27751358 PMID:28211887 PMID:28492532 PMID:28727877 PMID:28779002 PMID:28802053 PMID:28873162 PMID:29520813 PMID:29902706 PMID:29958926 PMID:30322717 PMID:30426508 PMID:30676620 PMID:30927251 PMID:31159747 PMID:31263571 PMID:31360903 PMID:31447099 PMID:31843900 PMID:32295079 PMID:32338768 PMID:32546565 PMID:32875559 PMID:32885271 PMID:33030641 PMID:33077847 PMID:33726816 PMID:33804961 PMID:34308366 PMID:34570182 PMID:34992046
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