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GENE - TERM ANNOTATION REPORT

RGD ID: 1609861
Species: Mus musculus
RGD Object: Gene
Symbol: mt-Nd3
Name: NADH dehydrogenase 3, mitochondrial
Acc ID: GO:0005747
Term: mitochondrial respiratory chain complex I
Definition: A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
Definition Source(s): GOC:mtg_sensu, ISBN:0198547684
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
mt-Nd3located_inISOMT-ND3 (Homo sapiens)9068941ComplexPortal PMID:28844695

PMID:28844695
mt-Nd3part_ofIBAPANTHER:PTN000114846 or UniProtKB:P03898 or FB:FBgn0013681 or UniProtKB:P038972290270GO_Central GO_REF:0000033
mt-Nd3part_ofISOUniProtKB:P038972290270MGI GO_REF:0000119 MGI:4834177
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