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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1607668
Species: Mus musculus
RGD Object: Gene
Symbol: Mir26a-1
Name: microRNA 26a-1
Acc ID: CHEBI:53181
Term: pristane
Definition: A norterpene that is an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group.
Chemical ID: MESH:C009042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir26a-1affects expressionISOMir26a (Rattus norvegicus)6480464CTDpristane affects the expression of MIR26A mRNAPMID:24423102
Mir26a-1multiple interactionsISOMir26a (Rattus norvegicus)6480464CTDMethotrexate inhibits the reaction [pristane results in decreased expression of MIR26A mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of IFNB1 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TLR3 protein]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF mRNA]; MIR26A mRNA inhibits the reaction [pristane results in increased expression of TNF protein]PMID:24423102
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