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GENE - TERM ANNOTATION REPORT

RGD ID: 1594539
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ang
Name: angiogenin
Acc ID: DOID:332
Term: amyotrophic lateral sclerosis
Definition: A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Amyotrophic_lateral_sclerosis "DO" "DO", http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_ALS.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ang ISOANG (Homo sapiens)6892707RGDDNA:mutations:multiple 
Ang ISOANG (Homo sapiens)6892713RGDprotein:increased expression:cerebrospinal fluid 
Ang ISOANG (Homo sapiens)6892718RGDDNA:missense mutations 
Angno_associationISOANG (Homo sapiens)6892716RGDDNA:missense mutation, SNPs: :p.I46V, rs11701, rs2228653 (human) 
Ang ISOANG (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Amyotrophic lateral sclerosisPMID:25741868
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