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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1561496
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Edem3
Name: ER degradation enhancing alpha-mannosidase like protein 3
Acc ID: CHEBI:7549
Term: N(gamma)-nitro-L-arginine methyl ester
Definition: An alpha-amino acid ester that is the methyl ester of N(gamma)-nitro-L-arginine.
Chemical ID: MESH:D019331
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Edem3multiple interactionsISOEdem3 (Mus musculus)6480464CTD[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 proteinPMID:38282657
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