GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccar1 | increases expression | ISO | CCAR1 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in increased expression of CCAR1 protein | PMID:23826121 PMID:30769864 | Ccar1 | multiple interactions | ISO | CCAR1 (Homo sapiens) | 6480464 | CTD | [Doxorubicin co-treated with JNK-IN-8] results in increased expression of CCAR1 protein; CCAR1 protein affects the reaction [Doxorubicin results in increased activity of CASP2 protein]; CCAR1 protein affects the reaction [Doxorubicin results in increased activity of CASP3 protein]; CCAR1 protein affects the reaction [Doxorubicin results in increased activity of CASP8 protein]; CCAR1 protein affects the reaction [Doxorubicin results in increased activity of CASP9 protein]; CCAR1 protein affects the reaction [Doxorubicin results in increased expression of H2AX protein]; CCAR1 protein affects the reaction [Doxorubicin results in increased phosphorylation of IKBKG protein]; CCAR1 protein affects the reaction [Doxorubicin results in increased phosphorylation of RELA protein]; Doxorubicin promotes the reaction [CCAR1 protein binds to ANAPC2 protein]; Doxorubicin promotes the reaction [CCAR1 protein binds to H2AX protein] | PMID:21903591 PMID:30769864 PMID:32024692 | | ||||||||||||||||||||||
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