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GENE - TERM ANNOTATION REPORT

RGD ID: 1552917
Species: Mus musculus
RGD Object: Gene
Symbol: C6
Name: complement component 6
Acc ID: GO:0006956
Term: complement activation
Definition: Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
Definition Source(s): GO_REF:0000022, GOC:add, ISBN:0781735149
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
C6involved_inIBAPANTHER:PTN001832474 or UniProtKB:P07357 or UniProtKB:P136712290270GO_Central GO_REF:0000033
C6involved_inISOUniProtKB:P136712290270MGI GO_REF:0000119 MGI:4834177
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