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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551988
Species: Mus musculus
RGD Object: Gene
Symbol: Parp1
Name: poly (ADP-ribose) polymerase family, member 1
Acc ID: CHEBI:16325
Term: lithocholic acid
Definition: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
Chemical ID: MESH:D008095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Parp1increases activityISOPARP1 (Homo sapiens)6480464CTDLithocholic Acid analog results in increased activity of PARP1 proteinPMID:2120135
Parp1multiple interactionsISOPARP1 (Homo sapiens)6480464CTD3-aminobenzamide inhibits the reaction [Lithocholic Acid analog results in increased activity of PARP1 protein]PMID:2120135
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