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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550101
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1b8
Name: aldo-keto reductase family 1, member B8
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b8multiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of AKR1B8 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of AKR1B8 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of AKR1B8 mRNA]PMID:19555225 PMID:34911549
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