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GENE - TERM ANNOTATION REPORT

RGD ID: 14206283
Species: Sus scrofa
RGD Object: Gene
Symbol: RAB8B
Name: RAB8B, member RAS oncogene family
Acc ID: GO:0006887
Term: exocytosis
Definition: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
Definition Source(s): GOC:mah, ISBN:0716731363, PMID:22323285
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RAB8Binvolved_inIBACGD:CAL0000186445 or MGI:97843 or PANTHER:PTN004664821 or PomBase:SPAC9E9.07c or Rab3a (Rattus norvegicus) or SGD:S000001889 or UniProtKB:P20336 or UniProtKB:P61006 or UniProtKB:P61026 or WB:WBGene00004273 or dictyBase:DDB_G0280043150520179GO_Central GO_REF:0000033
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