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GENE - TERM ANNOTATION REPORT

RGD ID: 14086633
Species: Sus scrofa
RGD Object: Gene
Symbol: GIP
Name: gastric inhibitory polypeptide
Acc ID: GO:0007189
Term: adenylate cyclase-activating G protein-coupled receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GIPinvolved_inIDA 150520179BHF-UCL PMID:26572091

PMID:26572091
GIPinvolved_inIEAUniProtKB:P09681 or UniProtKB:P48756 or ensembl:ENSMUSP00000099446 or ensembl:ENSP00000350005150520179Ensembl GO_REF:0000107
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