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GENE - TERM ANNOTATION REPORT

RGD ID: 1349504
Species: Homo sapiens
RGD Object: Gene
Symbol: U2AF1
Name: U2 small nuclear RNA auxiliary factor 1
Acc ID: GO:0005681
Term: spliceosomal complex
Definition: Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
Definition Source(s): GOC:editors, GOC:mah, ISBN:0198547684, PMID:19239890
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
U2AF1located_inIPI 150520179ComplexPortal PMID:11551507

PMID:11551507
U2AF1part_ofIBAMGI:98885 or PANTHER:PTN000289700 or PomBase:SPAP8A3.06 or UniProtKB:Q01081 or UniProtKB:Q15696150520179GO_Central GO_REF:0000033
U2AF1part_ofIDA 150520179HGNC-UCL PMID:9731529

PMID:9731529
U2AF1part_ofIEAPANTHER:PTHR12620:SF11150520179TreeGrafter GO_REF:0000118
U2AF1part_ofIEAUniProtKB-KW:KW-0747150520179UniProt GO_REF:0000043
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